Product Introduction
This product is used to detect concentration of cardiac troponin I (cTnI) in human serum,plasma or whole blood. The troponin complex, consisting of cTnI, troponin T (TnT) and troponin C (TnC), can adjust the interaction between actin and myosin. Concentration of cTnI is pretty low in healthy human blood. However, when acute myocardium infarction occurs, cTnI is released into blood quickly, which leads to rapid increase of cTnI concentration in hours and last 6 to 10 days. Therefore, blood cTnI concentration is regarded as a marker for myocardial infarction[1-3].
Production Specification
| Specimen Types | WB/Serum/Plasma |
| Specimen Capacity | WB:60μL; Serum/Plasma:40μL |
| Reaction Time | 15 min |
| Sample Capacity | 80μL |
| Detection Range | 20-40000ng/mL |
Advantages
● Rapid: Results in 15 mins
● Easy & Convenient: Easy operation and no need for extra equipment
● Room temperature to store
Clinical significance
❖ Rapid Quantitative Test quantify the concentration of cTnI by fluorescent immunoassay.
❖ It is used as an aid detection of myocardial Infarction.
Application
ICU, Respiratory Medicine, Emergency Department, Cardiology, Laboratory, emergency care
Reference
1. Le Tao. The clinical application and evaluation of the Triad rapid diagnosis to myocardial infarction. Journal of Chinese Clinical Medicine. 2005, 140: 15239- 15240.
2. Albert JS, Thygesen K, Antman E, Bassand JP. Myocarddial infarction redefined—a consensus document of the Joint European Society of Cardiology/American College of Cardiology Committee for the Redefinition of Myocardial Infarction.
3. Bernadette Cummins B. Sc. Margaret Lucy Auckland B. Sc. Peter Cummins Ph.D. Cardiac-specific troponin-l radioimmunoassay in the diagnosis of acute myocardial infarction[J]. Journal of American Heart. 1987, 113:1333-1344.
4. Hansen JH. HAMA Interfernce with Murine Monoclonal Antibody-Based Imminoassays [J]. J of Clinical Immunoassay. 1993.16: 294-299.
