Product Introduction
The creatine troponin complex, formed by cardiac muscle creatine troponin I (cTnI), troponin T (TnT), and troponin C (TnC), can adjust the interaction between actin and myosin. The concentration of cTnI is rare low in healthy human blood; However, when acute myocardium infarction occurs, the cTnI is released into the blood quickly and the concentration of cTnI increases from the fourth hour to the sixth hours, which can maintain 6 days to 10 days. Therefore, cTnI is regarded as a marker for myocardial infarction.
Creatine Kinase(CK) is a dimer existing as three isoenzymes. CK mainly exists in skeletal muscle, cardiac muscle, and brain tissue. There are three types of isoenzymes, including BB (brain type), MM (skeleton-type), and MB(hybridization type). The level of CK- MB in the blood is abnormal after the fourth hour to the sixth hour with the symptom of acute myocardial infarction; furthermore, it reaches its peak at the 18th-24th hour and recovers to its normal level after the second or the third day. Thus CK-MB is regarded as a marker for acute myocardial infarction.
Myo is a plasmon of low molecular weight, whose speed released is faster than another label of the heart muscle when the heart is hurt. Its concentration exceeds the normal level after 1 hour and reaches a peak after the fourth or the eighth hour when faced with myocardial infarction. Therefore, Myo is regarded as a marker for early acute myocardial infarction.
Product Specification
| Specimen Types |
WB/Plasma |
| Specimen Capacity |
WB:80μL; Plasma:50μL |
| Reaction Time |
15 min |
| Sample Capacity |
80μL |
| Clinical Significance |
cTnI>0.3ng/mL;
Myo>55ng/mL;
CK-MB>5ng/mL High risk of MI |
Advantages
√ Equipped with special dropper consumables, the operation is easier and more suitable for clinical use
√ Low sample requirements: whole blood can be processed without centrifugation
√ 3 in 1 (cTnI/CK-MB/Myo) detections improve the sensitivity and accuracy of results and reduce misdiagnosis caused by window reasons
Clinical significance
√ 3 in 1 (cTnI/CK-MB/Myo) detection has high sensitivity, better specificity, and more accurate results
√ Assess the area of myocardial infarction, detect reperfusion and recurrence of myocardial infarction, etc.
√ As an important indicator of brain injury, nervous system disease, carbon monoxide poisoning diagnosis, and treatment effect evaluation
Application
ICU, Respiratory Medicine, Emergency Department, Cardiology, Laboratory, Emergency Car
